Brain Size May Predict Alzheimer’s Risk Years Before Symptoms Appear

US scientists have found brain scans measuring the thickness of certain regions of the brain may help identify people who have a higher risk of developing Alzheimer’s disease. Researchers at Massachusetts General Hospital, in Boston, and the University of Pennsylvania, in Philadelphia, studied MRI scans from 159 cognitively normal older … Continue reading

Cambridgeshire Big Walk Huge Success for Alzheimer’s Research UK

Alzheimer’s Research UK’s Big Walk on Sunday 13 May was a huge success, and on target to raise thousands of pounds for pioneering dementia research. Shirley Cramer CBE, Chief Executive of the UK’s leading dementia research charity, cut the ribbon to mark the start of the nine mile circular walk … Continue reading

Retinal Damage Linked to Cognitive Decline

US scientists have found that women with retinal damage are more likely to show signs of cognitive decline and vascular damage in the brain. The study is published in the journal Neurology. Research led at the University of California studied 511 women with an average age of 69, who were enrolled … Continue reading

Common Alzheimer’s Drug May Benefit Patients in Later Stages of Disease

UK scientists have found that the drug donepezil, which is approved for use only in the mild to moderate stages of Alzheimer’s disease, could benefit patients in the later stages of the disease. The study is published in the New England Journal of Medicine. The study, led by researchers at King’s … Continue reading

Scientists Discover How Sugars Control Hallmark Alzheimer’s Protein

A study by scientists in Canada and the US has shown that a chemical change to a hallmark Alzheimer’s protein, tau, can stop it from forming toxic tangles – a characteristic of the disease. The findings, published online on 26 February in the journal Nature Chemical Biology, open up new … Continue reading

Edinburgh Study Could Bring Early Alzheimer’s Diagnosis a Step Closer

Scientists in Edinburgh have found particles in cerebrospinal fluid (CSF) that could be harnessed to identify changes in the brain that occur during Alzheimer’s disease. The study, which was part-funded by Alzheimer’s Research UK, could pave the way for a new test to diagnose the disease in its earliest stages. … Continue reading

Low Omega-3 Fatty Acid Levels Linked to Markers of Brain Ageing

Scientists in the US have linked low levels of the omega-3 fatty acid, docosahexaenoic acid (DHA), to lower scores on cognitive tests and lower brain volume. The study is published in the journal Neurology. Researchers at the University of California in Los Angeles studied blood samples from 1,575 cognitively healthy people, … Continue reading

Councillor Tony Orgee Backs Alzheimer’s Research UK’s Big Walk

The Chairman of South Cambridgeshire District Council, Cllr Tony Orgee, is urging everyone to take part in Alzheimer’s Research UK’s Big Walk in the county on Sunday 13 May. The UK’s leading dementia research charity, based in Great Shelford, aims to raise £50,000 for pioneering dementia research. Hundreds of people … Continue reading

Specific Antipsychotic Drugs Increase Risk of Death in Elderly

US scientists have found certain antipsychotic drugs increase the risk of death in elderly nursing home patients, when compared with other antipsychotics. The study is published in the BMJ online. Researchers at Harvard Medical School studied medical records from 75,445 people over 65 who were living in nursing homes. They assessed … Continue reading

Sleep Disruption Linked to Early Alzheimer’s Markers

Scientists in the US have found cognitively healthy people with disrupted sleep patterns may be more likely to have markers associated with early Alzheimer’s disease. The study is due to be presented at the American Academy of Neurology’s 64th Annual Meeting in April. Researchers at Washington University School of Medicine, in St … Continue reading

Specific Antibodies Halt Alzheimer’s in Mice

Antibodies that block the process of synapse disintegration in Alzheimer’s disease have been identified, raising hopes for the development of a treatment to combat early cognitive decline in the disease. During Alzheimer’s, a protein called amyloid-beta builds in the brain and causes the loss of synapses – the connections between … Continue reading

Cancer Drug Clears Alzheimer’s Protein and Improves Cognition in Mice

US scientists have found that a skin cancer drug is able to clear a known Alzheimer’s protein, amyloid, from the brains of mice. The study, which also showed the mice had cognitive improvements, is published in the journal Science. Researchers at Case Western University studied the effects of a drug called … Continue reading

Councillor Tony Orgee Backs Alzheimer’s Research UK’s Big Walk

The Chairman of South Cambridgeshire District Council, Cllr Tony Orgee, is urging everyone to take part in Alzheimer’s Research UK’s Big Walk in the county on Sunday 13 May. The UK’s leading dementia research charity, based in Great Shelford, aims to raise £50,000 for pioneering dementia research. Hundreds of people … Continue reading

Cambs Charity Receives Grant From Million Dollar Round Table Foundation

Great Shelford-based charity, Alzheimer’s Research UK, has received a boost of $10,000 (equivalent to £6,100) from the Million Dollar Round Table Foundation (MDRT) in America. This grant is thanks to Simon Gibson, a Cambridgeshire supporter of the UK’s leading dementia research charity. He attended the cheque presentation, which took place … Continue reading

UK’s Largest Dementia Research Conference Comes to Birmingham in 2012

Over 250 leading dementia scientists from across the globe will gather in Birmingham this week for Alzheimer’s Research UK Conference 2012, the country’s largest dedicated dementia research conference. The event, which takes place on 27 and 28 March, will share the latest evidence on a wide range of research topics, … Continue reading

Virtual Reality Exercise Games May Improve Cognition in Older Adults

Scientists in the US today revealed the finding of a clinical trial investigating the effects of “exergaming”, or virtual reality-enhanced exercise, on cognition in a group of older adults. The study, one of the first trials of its kind, showed greater cognitive benefit for those who played exergames than those … Continue reading

Coleraine Researchers Find New Drugs Boost Brain Cell Growth

Scientists in Northern Ireland have found drugs that mimic some of the actions of insulin may encourage the growth of new brain cells. It’s hoped the study, funded by Alzheimer’s Research UK, could pave the way for the design of new treatments for Alzheimer’s disease. Researchers at the University of … Continue reading

Nicotine Patches May Slow Progression to Alzheimer’s

Scientists in the US today announced clinical trial results showing that nicotine patches may improve cognitive performance in elderly people with early memory problems. The findings could take scientists a step closer to the development of new treatments to tackle dementia. The study, published in the journal Neurology, was completed … Continue reading

Stacey Solomon Gets It Right for Cambs Charity in Who Wants to Be a Millionaire

Stacey Solomon, who shot to fame in The X Factor in 2009, has won £12,500 for Great Shelford-based Alzheimer’s Research UK, on ITV’s Who Wants To Be A Millionaire. Stacey sat in the hot seat for the Celebrity New Year Special, broadcast on Tuesday 3 January, and teamed up with … Continue reading

Stem Cell Technology Reveals Clues to Alzheimer’s

Scientists in the US have used stem cells from patients to overcome the challenge of obtaining live brain cells, allowing them to learn more about the causes of Alzheimer’s. The study, published online today in the journal Nature, provides new opportunities for scientists to model the complex disease. Induced pluripotent … Continue reading

Bath Scientists Secure £220k Funding Boost for Dementia Research

A major research project into the role of iron in dementia with Lewy bodies is getting underway in Bath, thanks to grants worth £220,500 from two charities dedicated to funding dementia research. Alzheimer’s Research UK and Alzheimer’s research charity BRACE have teamed up to fund a unique three-year project that … Continue reading

Cambridge Scientists Use Down’s Syndrome Stem Cells to Model Alzheimer’s

Scientists at the University of Cambridge have developed a new and innovative way to study Alzheimer’s disease in the lab. The stem cell technique, which allows researchers to track the disease over a matter of weeks, could provide a valuable tool for scientists to unravel the complexity of Alzheimer’s and … Continue reading

Uk Scientists Uncover New Clues for Early Diagnosis of Alzheimer’s

Scientists in Nottingham have found abnormal levels of seven different proteins in spinal fluid could act as markers for detecting Alzheimer’s disease. The study, which was part-funded by Alzheimer’s Research UK, the UK’s leading dementia research charity, could lead to the development of a new test to detect the disease … Continue reading

Virtual Reality Exercise Games May Improve Cognition in Older Adults

Scientists in the US revealed the finding of a clinical trial investigating the effects of “exergaming”, or virtual reality-enhanced exercise, on cognition in a group of older adults. The study, one of the first trials of its kind, showed greater cognitive benefit for those who played exergames than those who took … Continue reading

Men at Higher Risk of Mild Memory Loss in Old Age

US scientists have found that men may be at higher risk than women of mild cognitive impairment – a stage that often precedes dementia. The study is published online in the journal Neurology. Researchers from the Mayo Clinic in Rochester, Minnesota, studied 1,450 people between the ages of 70 and 89, … Continue reading

More White Coats: Capacity Boost the Only Answer to Uk Dementia Crisis

Alzheimer’s Research UK has challenged Government to avoid flash in the pan tactics on dementia research and commit to a national dementia research strategy. In a new report – Defeating Dementia – the UK’s leading dementia research charity warns that the UK’s world-renowned dementia knowledge base could be lost unless … Continue reading